The facts about high fructose corn syrup.

NEWS

"The Sugar Fix" Statement

"King Corn" Statement

High Fructose Corn Syrup Natural Labeling Statement

NEW RESEARCH

Researchers Find Beverages Sweetened with HFCS and Sugar Have Similar Impact on Feelings of Fullness

Study Finds HFCS and Sugar Affect Feelings of Fullness and Uric Acid Similarly

Experts Conclude Evidence Lacking to Implicate High Fructose Corn Syrup as a Unique Cause of Obesity

Study Finds HFCS and Sucrose Affect Blood Glucose, Insulin, Leptin and Ghrelin Similarly

MORE RESEARCH

NEW ARTICLES

Much ado about high-fructose corn syrup in beverages: the meat of the matter

Weak Association Between Sweeteners or Sweetened Beverages and Diabetes

"The Sugar Fix" Statement"King Corn" StatementHigh Fructose Corn Syrup Natural Labeling StatementResearchers Find Beverages Sweetened with HFCS and Sugar Have Similar Impact on Feelings of FullnessStudy Finds HFCS and Sugar Affect Feelings of Fullness and Uric Acid SimilarlyExperts Conclude Evidence Lacking to Implicate High Fructose Corn Syrup as a Unique Cause of ObesityStudy Finds HFCS and Sucrose Affect Blood Glucose, Insulin, Leptin and Ghrelin SimilarlyMORE RESEARCHResearchers Find Beverages Sweetened with HFCS and Sucrose Affect Satiety SimilarlyStudy Finds Frequent Soft Drink Consumption Does Not Lead to Higher Obesity RatesResearchers Find HFCS and Sucrose Affect Uric Acid SimilarlyResearchers Find HFCS and Sucrose Affect Triglycerides SimilarlyHigh Fructose Corn Syrups, Part 1: Composition, Consumption, and MetabolismHigh Fructose Corn Syrups, Part 2: Health EffectsHighs and Lows of High Fructose Corn Syrup: A Report From the Center for Food and Nutrition Policy and Its Ceres ® WorkshopMuch ado about high-fructose corn syrup in beverages: the meat of the matterWeak Association Between Sweeteners or Sweetened Beverages and DiabetesArticlesFood Processing Article Provides Perspective on Science and HFCSCommentary in The Washington Times Puts Nutritional Advice Into PerspectiveFood Technology Article Provides Perspective on HFCS MythsNew York Times Article Reviews The Science - HFCS Myths DebunkedNutrition Today Articles Bring Much-Needed Perspective to HFCS in the Obesity DebateHFCS BasicsWhat is high fructose corn syrup?Per Capita Consumption of HFCSHFCS Is NaturalWhat the Experts Say About HFCSTop Published Myths About HFCSUses/BenefitsConsumer benefits of HFCSUses of HFCSHFCS Q & AWhat is the difference between HFCS and table sugar?Is HFCS a "natural" sweetener?Is HFCS sweeter than sugar?Is there a correlation between the introduction of HFCS and the rise of obesity in the past 30 years?Has the use of HFCS in the food supply increased the amount of fructose in the diet?Does consumption of HFCS, as compared to sucrose, reduce the ability of the body to produce insulin?Does the body process HFCS differently than other sugars?Is HFCS considered a safe food ingredient?Does HFCS have a high Glycemic Index?Is HFCS allergenic?How does HFCS serve as a flavor enhancer?How is HFCS made?Nutrition Today Articles Bring Much-Needed Perspective to HFCS in the Obesity DebateResearchers Find HFCS and Sucrose Affect Uric Acid SimilarlyResearchers Find HFCS and Sucrose Affect Triglycerides SimilarlyScientific Experts Conclude HFCS Is NOT A Unique Contributor to ObesityWhat is the Role of Physical Activity in a Balanced Diet?HomeFootnotesTerms of UsePrivacy Policy

What is the difference between HFCS and table sugar?

From the perspective of the human body, there is very little difference between table sugar (sucrose) and high fructose corn syrup. Sucrose and high fructose corn syrup have the same caloric density as most carbohydrates; both contribute 4 calories per gram. In terms of chemical structure, sucrose and high fructose corn syrup differ by the bonding of their sugars. Sucrose is a disaccharide, in which fructose and glucose are linked by a chemical bond. (3) Fructose and glucose are not bonded in high fructose corn syrup, and so are sometimes referred to as "free" sugars. Once the combination of glucose and fructose found in high fructose corn syrup and sucrose are absorbed into the blood stream, the two types of sweetener appear to be metabolized similarly using well-characterized metabolic pathways. (4,5)

Sucrose and high fructose corn syrup contain nearly the same one-to-one ratio of two sugars - fructose and glucose:

Sucrose is 50 percent fructose and 50 percent glucose.
High fructose corn syrup is sold principally in two formulations - 42 percent and 55 percent fructose - with the balance made up of primarily glucose and some higher sugars. (1)

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