The facts about high fructose corn syrup.

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NEW RESEARCH

Researchers Find Beverages Sweetened with HFCS and Sugar Have Similar Impact on Feelings of Fullness

Study Finds HFCS and Sugar Affect Feelings of Fullness and Uric Acid Similarly

Experts Conclude Evidence Lacking to Implicate High Fructose Corn Syrup as a Unique Cause of Obesity

Study Finds HFCS and Sucrose Affect Blood Glucose, Insulin, Leptin and Ghrelin Similarly

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"The Sugar Fix" Statement"King Corn" StatementHigh Fructose Corn Syrup Natural Labeling StatementResearchers Find Beverages Sweetened with HFCS and Sugar Have Similar Impact on Feelings of FullnessStudy Finds HFCS and Sugar Affect Feelings of Fullness and Uric Acid SimilarlyExperts Conclude Evidence Lacking to Implicate High Fructose Corn Syrup as a Unique Cause of ObesityStudy Finds HFCS and Sucrose Affect Blood Glucose, Insulin, Leptin and Ghrelin SimilarlyMORE RESEARCHResearchers Find Beverages Sweetened with HFCS and Sucrose Affect Satiety SimilarlyStudy Finds Frequent Soft Drink Consumption Does Not Lead to Higher Obesity RatesResearchers Find HFCS and Sucrose Affect Uric Acid SimilarlyResearchers Find HFCS and Sucrose Affect Triglycerides SimilarlyHigh Fructose Corn Syrups, Part 1: Composition, Consumption, and MetabolismHigh Fructose Corn Syrups, Part 2: Health EffectsHighs and Lows of High Fructose Corn Syrup: A Report From the Center for Food and Nutrition Policy and Its Ceres ® WorkshopMuch ado about high-fructose corn syrup in beverages: the meat of the matterWeak Association Between Sweeteners or Sweetened Beverages and DiabetesArticlesFood Processing Article Provides Perspective on Science and HFCSCommentary in The Washington Times Puts Nutritional Advice Into PerspectiveFood Technology Article Provides Perspective on HFCS MythsNew York Times Article Reviews The Science - HFCS Myths DebunkedNutrition Today Articles Bring Much-Needed Perspective to HFCS in the Obesity DebateHFCS BasicsWhat is high fructose corn syrup?Per Capita Consumption of HFCSHFCS Is NaturalWhat the Experts Say About HFCSTop Published Myths About HFCSUses/BenefitsConsumer benefits of HFCSUses of HFCSHFCS Q & AWhat is the difference between HFCS and table sugar?Is HFCS a "natural" sweetener?Is HFCS sweeter than sugar?Is there a correlation between the introduction of HFCS and the rise of obesity in the past 30 years?Has the use of HFCS in the food supply increased the amount of fructose in the diet?Does consumption of HFCS, as compared to sucrose, reduce the ability of the body to produce insulin?Does the body process HFCS differently than other sugars?Is HFCS considered a safe food ingredient?Does HFCS have a high Glycemic Index?Is HFCS allergenic?How does HFCS serve as a flavor enhancer?How is HFCS made?Nutrition Today Articles Bring Much-Needed Perspective to HFCS in the Obesity DebateResearchers Find HFCS and Sucrose Affect Uric Acid SimilarlyResearchers Find HFCS and Sucrose Affect Triglycerides SimilarlyScientific Experts Conclude HFCS Is NOT A Unique Contributor to ObesityWhat is the Role of Physical Activity in a Balanced Diet?HomeFootnotesTerms of UsePrivacy Policy

Researchers Find high fructose corn syrup and Sucrose Affect Uric Acid Similarly

A recent study by Joshua Lowndes, et al at the Rippe Lifestyle Institute reviewed the effects of high fructose corn syrup (HFCS) and sucrose on circulating levels of uric acid in a study group of lean women. Uric acid is believed to play a role in the development of the metabolic syndrome. This short-term study found "no differences in the metabolic effects in lean women [of high fructose corn syrup] compared to sucrose," and called for further similar studies of obese individuals and males.

Their paper was presented at the June 2007 meeting of The Endocrine Society. ("The Effect of High-Fructose Corn Syrup on Uric Acid Levels in Normal Weight Women" Program Abstract # P2-45)

An abstract of the study follows.

The Effect of High-Fructose Corn Syrup on Uric Acid Levels in Normal Weight Women.

Joshua Lowndes, Linda M Zukley, Von Nguyen, Theodore J Angelopoulos, James M Rippe, Rippe Lifestyle Inst, Celebration, FL

Over the past 3 decades dietary fructose consumption has increased greatly, a trend coinciding with the emergence of the obesity epidemic. As such, excess fructose consumption has been investigated for its potential causative roll. Recent evidence also suggests a potential link between fructose consumption and the development of the metabolic syndrome, independent of weight gain, as a result of uric acid mediated endothelial dysfunction. Over the past 30 years high fructose corn syrup has largely replaced sucrose as the sweetener in carbonated soft drinks (CSD) in the USA. The high fructose corn syrup in CSD represents a major source of fructose in the USA diet. Therefore the purpose of this study was to compare the effects of high fructose corn syrup when consumed as part of mixed meal, on uric acid levels compared to sucrose consumption.

Thirty normal weight women (mean age 33.0 10.6 years, mean BMI 22.42 1.65) were studied on two randomized 2-day experimental visits to our metabolic unit during which high fructose corn syrup and sucrose sweetened beverages were consumed with isocaloric diets on day 1 while blood was sampled. On day 2 of these visits, food was eaten ad libitum. Blood was sampled upon entering the metabolic unit at 9am, and two hours subsequently until 7am the following morning.

No significant differences between the two experimental visits were seen in fasting values of uric acid (p=NS) all of which were within normal limits. The within day variation was not different between the two experimental conditions (high fructose corn syrup/sucrose). A post-prandial increase in uric acid concentration was only observed after dinner (p=0.013), but this was comparable between the two trials. There were no differences in energy or macronutrient intake on day 2 (ad-libtum feeding).

These short-term results suggest that when fructose is consumed in the form of high fructose corn syrup, there are no differences in the metabolic effects in lean women compared to sucrose. Further research is required to determine if the current findings hold true for obese individuals and males.

The abstract is also available on the conference website.

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